Escort quests can take awhile to do. I have thoroughly tested all the escort quests in the game for time/xp. Most are worth doing, but as long as you are able to actually do them without failing. Most require you to pay special attention to the escortee as most are fragile and will die easily, so do your best to keep mobs off of the escortee during escort quests. The longest one in the game is the Tanaris chicken escort. The chicken escorts are only worth doing if you were able to do all 3 of them, as if you do, you will be able to turn in an additional easy quick XP turn in quest at BB, which makes them worth it.
Tyr's Hand (marked RED on the map) - One of the Scarlet Crusade's Bastions, the Tyr's Hand is located in the south-eastern part of the Eastern Plaguelands. Scarlet Crusade members that can be encountered there have a very good Loot Table. The main focus here will be the Scarlet Archmage (which is an Elite, so farming them solo might not be possible for some Classes). the Archmage drops a lot of Runecloth, ~14 Silver worth of Pocket Money on average, and most importantly, the Formula: Enchant Weapon - Crusader which is very valuable to all Enchanters and achieves really high prices on the Auction House. Mobs encountered in Tyr's Hand can be Pickpocketed, so this is a quite good spot for experienced Rogues. Recommended Level - 60 (some Classes might be required to find a Farming Partner and go in as a duo).
I made some route changes to the Horde levels 43-44 sections. I have swapped 44 Dustwallow Marsh with 44 Desolace (the entire sections). This allowed me to do Deadmire (at lvl 43 instead of 38) and then go stop at TB to turn in Deadmire + The Black Shield at the same time, then fly quickly to do the Desolace stuff. Doing 44 Desolace is now mandatory because I think its faster with the new routes. This will also make the level 53 grind much shorter. I think these were great changes.
Kurzen's Compound (marked BLUE on the map) - Colonel Kurzen was once a very talented Stormwind Officer. He was sent with an expedition to the Jungles of Stranglethorn, where he fell victim to Mai'Zoth, a powerful Ogre Mage and his foul magic. Majority of Colonel's troops are still loyal to him and provide Players with some valuable Loot. In this spot, you will encounter Kurzen Jungle Fighters, Kurzen Medicine Men, Kurzen Wranglers, and Kurzen Commandos. These Humanoids drop a lot of Silk Cloth (that can be generally turned into Bandages and Vendored), valuable Wool Cloth (the main source of Gold from this spot, check the AH prices), Fadeleaf (Medicine Men), Liferoot (Medicine Men), 12 Slot Bags (Commandos), Vendor Trash Items, and some Pocket Money. This spot is especially good for Rogues, as the ability to Pickpocket mobs will increase profits by a noticeable margin. Recommended Level - 34+ (36+ to be extra safe, as Humanoid mobs can be problematic because they tend to run away on low health and pull additional enemies).